“Astrocytes chewing tau aggregates in mouse brain”, submitted by Meghraj Baghel at the Philip C. Wong Lab
This image shows fluorescent staining in a mouse brain model of Alzheimer’s disease. The green fluorescence is phosphorylated tau tangles, red fluorescence is the astrocyte marker, GFAP. Co-localization suggests the astrocytes are taking up phospho-tau
to clear it from the brain. Alternatively, this interaction might trigger a pro-inflammatory response, contributing to disease progression and neurodegeneration.
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